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CHIRAL RESOLUTION SERVICE

Syncom has a unique set of over 200 resolving agents in house. Combined with the Dutch Resolution technique, it enables us to develop a classical resolution method with a success rate of over 97%. Syncom knows how to scan your racemate quickly and to obtain pure material with a high enantiomeric excess. The latter is nearly always the major barrier in a Pasteur resolution.

We also offer resolution by biocatalysis and chiral chromatography for the preparation of pure enantiomers.

 

We offer the following types of studies:

• Screening to Discover the Optimal Resolving Agent and Crystallization Solvent
• Classical Resolution of Racemates
• Scale-up of the Resolution Process
• Development of Selective Nucleation Inhibitors
• Conglomerate Screening
• Preferential Crystallization
• Ostwald Ripening
• Chiral Chromatography
• Determination and Interpretation of Phase Diagrams

 

Our chiral resolution service is also part of the 'Chirality First Time right' service.